Department of Chemistry, Columbia University
Software
Software
Software
Software
Software
Software
tMAVEN
tMAVEN
tMAVEN
tMAVEN
tMAVEN
tMAVEN
tMAVEN is a program for analyzing time series data from single-molecule experiments. It is fine-tuned for single-molecule fluorescence resonance energy transfer (smFRET) experiments. The major design goals are to allow for:
-
Extremely fast pre-processing
-
Perfectly reproducible figures (e.g., tick locations)
-
A one-stop-shop for kinetic modeling
-
Immutable data – you only work on a copy of it!
-
Power-user coding via scripts
tMAVEN can be downloaded here.
tMAVEN is a program for analyzing time series data from single-molecule experiments. It is fine-tuned for single-molecule fluorescence resonance energy transfer (smFRET) experiments. The major design goals are to allow for:
-
Extremely fast pre-processing
-
Perfectly reproducible figures (e.g., tick locations)
-
A one-stop-shop for kinetic modeling
-
Immutable data – you only work on a copy of it!
-
Power-user coding via scripts
tMAVEN can be downloaded here.
tMAVEN is a program for analyzing time series data from single-molecule experiments. It is fine-tuned for single-molecule fluorescence resonance energy transfer (smFRET) experiments. The major design goals are to allow for:
-
Extremely fast pre-processing
-
Perfectly reproducible figures (e.g., tick locations)
-
A one-stop-shop for kinetic modeling
-
Immutable data – you only work on a copy of it!
-
Power-user coding via scripts
tMAVEN can be downloaded here.
tMAVEN is a program for analyzing time series data from single-molecule experiments. It is fine-tuned for single-molecule fluorescence resonance energy transfer (smFRET) experiments. The major design goals are to allow for:
-
Extremely fast pre-processing
-
Perfectly reproducible figures (e.g., tick locations)
-
A one-stop-shop for kinetic modeling
-
Immutable data – you only work on a copy of it!
-
Power-user coding via scripts
tMAVEN can be downloaded here.
tMAVEN is a program for analyzing time series data from single-molecule experiments. It is fine-tuned for single-molecule fluorescence resonance energy transfer (smFRET) experiments. The major design goals are to allow for:
-
Extremely fast pre-processing
-
Perfectly reproducible figures (e.g., tick locations)
-
A one-stop-shop for kinetic modeling
-
Immutable data – you only work on a copy of it!
-
Power-user coding via scripts
tMAVEN can be downloaded here.
tMAVEN is a program for analyzing time series data from single-molecule experiments. It is fine-tuned for single-molecule fluorescence resonance energy transfer (smFRET) experiments. The major design goals are to allow for:
-
Extremely fast pre-processing
-
Perfectly reproducible figures (e.g., tick locations)
-
A one-stop-shop for kinetic modeling
-
Immutable data – you only work on a copy of it!
-
Power-user coding via scripts
tMAVEN can be downloaded here.
Older software
vbFRET
vbFRET uses variational Bayesian inference to learn hidden Markov models from individual, single-molecule fluorescence resonance energy transfer efficiency (EFRET) versus time trajectories as described in Bronson et al (2009) and Bronson et al (2010). The software is implemented in MATLAB and can be downloaded here.

ebFRET
ebFRET uses empirical Bayesian inference to learn a single, consensus hidden Markov model from a large population of single-molecule fluorescence resonance energy transfer efficiency (EFRET) versus time trajectories as described in van de Meent et al (2013) and van de Meent et al (2014). The software is implemented in MATLAB and can be downloaded here.
